By James C. Bobrow MD
Reports the anatomy, body structure, embryology and pathology of the lens. Covers the epidemiology, assessment and administration of cataracts; offers an outline of lens and cataract surgical procedure; and explores the problems and certain occasions of cataract surgical procedure. final significant revision 2008 2009.
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Extra info for 2011-2012 Basic and Clinical Science Course, Section 11: Lens and Cataract (Basic & Clinical Science Course)
As the fiber cells mature, their nuclei and other membrane-bound organelles undergo degradation, a process that reduces light scattering. The primary lens fibers make up the embryonic nucleus that will ultimately occupy the central area of the lens in adu lt life. The cells of the anterior lens vesicle remai n as a monolayer of cuboidal cells, the lens epithelium. Subsequent growth of the lens is due to proliferation within the epithelium. CHAPTER 4, Embryology. 27 epithelium Lens capsule Primary lens fibers (embryonic nucleus) F.
The epithelial cells near the lens equator elongate to form secondary lens fibers. The anterior aspect of each developing lens fiber extends anteriorly beneath the lens epithelium. towa rd the anterior pole of the lens. The posterior aspect of each developing lens fiber extends posteriorly along the capsule toward the posterior pole of the lens. In this manner. new lens fibers are continually formed . laye r upon layer. As each 28 • Lens and Cataract secondary fiber cell detaches from the capsule, it loses its nucleus and membrane-bound organelles.
Occasionally, a small perforating injury of the lens capsule may heal, resultin g in a stationary focal cortical cataract (Fig 5-13) . Radiation Ionizing radiation The lens is extre mely sensitive to ionizing radiation; however, as much as 20 years may pass after exposure before a cataract becom es clinically appare nt. This period of latency is relate d to th e dose of radiation an d to th e patient's age; younge r patients are more susceptible because they have more ac tively growing lens cells.
2011-2012 Basic and Clinical Science Course, Section 11: Lens and Cataract (Basic & Clinical Science Course) by James C. Bobrow MD